II.
EDUCATION AND QUALIFICATIONS
Senior lecturer, Discipline: Immunology, Victor Babes University of
Medicine and Pharmacy, Timisoara
Specialist: Immunology, Clinical laboratory
III.
AREAS OF INTEREST IN RESEARCH
Etiology of Balkan endemic nephropathy, geomedicine (medical geology)
IV.
SCIENTIFIC AWARDS
Two First Prizes: National Biology Contest (1989, Romania)
Becton Dickinson fellowship for training in flow-cytometry -12/1993,
Heidelberg, Germany
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GRANTS
CLG NATO grants: 2001, 2002, 2003 for research on the Balkan endemic
nephropathy
IV.
AFFILIATION TO PROFESSIONAL ASSOCIATIONS
Member of the Romanian Society of Immunology
Member and official adviser of the International Working Group of Medical
Geology
VIII.
WORKS PUBLISHED
5 books, 14 articles published in indexed reviews, and 25 papers presented
at scientific conventions
BOOKS:
Organic Compounds Derived from Pliocene Lignite and the Etiology
of Balkan Endemic Nephropathy, Geology and Health: Closing the Gap
Tatu, CA, Orem WH et al. (2003), (Skinner HCW, Berger AR, eds.), Oxford
University Press, Oxford.
ARTICLES:
1. Health Effects from Toxic
Organic Compounds from Coal: from Romania to Powder River Basin
Orem, W.H., Tatu, C.A., et al.(2003), Wyoming, Medical Geology Newsletter
No.7. , Uppsala, Sweden.
2. Health Impacts of Coal and
Coal Use: Possible Solutions
Robert B. Finkelman, William Orem, Vincent Castranova, Calin A. Tatu,
Harvey E. Belkin, Baoshan Zheng, Harry E. Lerch, Susan V. Maharaj, Anne
L. Bates (2002) , International Journal of Coal Geology 50: 425- 443
3. Environment, Geochemistry,
and the Etiology of Balkan Endemic Nephropathy: Lessons from Romania
Orem W.H., Tatu C.A., Feder G.L., Finkelman R.B., Lerch H.E., Maharaj
S., Szilagyi D., Dumitrascu V., Paunescu V. and Margineanu, F.(2002),
Facta Universitatis, Medicine and Biology 9, 39-46.
4. Weathered Coal Deposits and
Balkan Endemic Nephropathy
Feder G.L., Tatu C.A., Orem W.H., Paunescu V., Dumitrascu V., Szilagyi
D., Finkelman R.B., Margineanu F., Schneider F.: 2002, , Facta Universitatis,
Medicine and Biology 9,34-38.
5. Health Effects of Toxic Organic
Compounds from Coal: the Case of Balkan Endemic Nephropathy (BEN)
Orem W.H., Tatu C.A, US Geological Survey Fact Sheet 004-01, April 2001.
6. Selective Maturation of VH12
B Cells in the Spleen Enriches for Anti-phosphatidyl Choline B Cells:
Evidence for Receptor Editing
Tatu C, Clarke SH (2000), Curr Top Microbiol Immunol, 252:77-86.
7. Selection at Multiple Checkpoints
Focuses V(H)12 B Cell
Differentiation toward a Single B-1 Cell Specificity
Tatu C., Ye J., Arnold L.W., Clarke S.H. (1999), J Exp Med., 190: 903-914.
8. Identification of a Precursor
to Phosphatidyl Choline-specific B-1 Cells Suggesting that B-1 Cells
Differentiate from Splenic Conventional B Cells in Vivo: Cyclosporin
A Blocks Differentiation to B-1
Arnold L.W., McCray S.K., Tatu C., Clarke S.H. (2000), J. Immunol.,
164: 2924-2930.
9. Additional Support for the
Role of the Pliocene Lignite Derived Organic Compounds in the Etiology
of Balkan Endemic Nephropathy
Tatu C.A., Orem W.H., Feder G.L., Finkelman R.B., Szilagyi D.N., Dumitrascu
V, Margineanu F., Paunescu, V.(2000), J. Med. Biochem., 4: 95-101.
10. Balkan Endemic Nephropathy
Etiology: a Link to the Geological Environment
Tatu C.A., Orem W.H., Feder G.L., Paunescu V., Dumitrascu V., Szilagyi
D.N., Finkelman R.B., Margineanu F., Schneider F.: (2000), Central European
Journal of Occupational and Environmental Medicine 6,138-150.
11. The Etiology of Balkan Endemic
Nephropathy: Still More Questions than Answers
Tatu C. A., Orem W. H., Finkelman R. B., Feder G. L. (1998), Environ.
Health Perspect. 106:689-700.
12. Balkan Nephropathy, the Haematopoietic
System and the Environmental Connection
Tatu C. A., Drugarin D, Paunescu V, Stanescu D. I., Schneider F. (1998),
, Food Chem Toxicol 36:245-247.
13. Immunologic Tolerance: Self-nonself
Discrimination vs. Costimulatory Factors and Second Signals
Simon Z, Tatu C. A., (1998), , Med Hypotheses 51:1-3.
14. P glycoprotein Mediated
Multidrug Resistance
Assessment by Flow cytometry in Malignant Hemopathies, Anticancer Res
Tatu C. A., Paunescu V, Stanescu D. I., Schneider Fr (1997), 17:2583
2586.
Department
