IOANA RALUCA SISKA
I. PERSONAL DETAILS
Family name: SISKA
First name: IOANA RALUCA
Date of birth: 12.10.1965
E-mail: isiska@umft.ro

II. EDUCATION AND QUALIFICATIONS
Senior lecturer, Dept. of Physiology, Victor Babes University of Medicine and Pharmacy, Timisoara,
2000: MD, Functional Explorations
2003: Specialist, Laboratory Medicine
2001: PhD in Medicine, speciality: normal and pathological physiology, Timisoara Research Centre, dissertation: 'Reactivity of Venous Smooth Muscle'

III. AREAS OF INTEREST IN RESEARCH
Physiology and physiopathology of vascular venous muscle with focus on the study of the reactivity of the venous smooth muscle
Within the discipline, I completed the experimental model of investigation of the reactivity of the smooth muscle of the human saphenous vein; the model set up the basis for my PhD dissertation;
The analysis of the parameters of the capacity of antioxidant defence of blood (superoxidedismutasis and reduced glutathione) in the varicose disease;
The physiology and physiopathology of venous circulation;
In parallel, I took part as a member of the work group in the studies developed within the discipline dealing with the reactivity of the tracheo-bronchial smooth muscle at rats, guinea pigs, and humans.
In collaboration with Prof. Dr. Virgil Paunescu, upon a short visit at the University of Medicine from Marseilles, France (July 2001), I contributed to the initiation of a culture of endothelial cells of human umbilical vein at the laboratory of the Centre of Immunophysiology and Biotechnologies from Timisoara;
The study of plasticization of human stem cells: the research of endothelial stem cells and of the transdifferentiation of the stem cell in cardyomyocyte.

III. GRANTS
Collaboration on contract-based scientific research projects
1. Pre-clinic and clinic research on the Romanian product Antagonic-stress
Research contract with POLGEC SRL, Bucharest
Contract value: 2.900.000 lei
Coordinator: Prof. Schneider F., MD, PhD
2. Immuno-allergic Implications
1992 - 1995, Research contract with the Academy of Medical Sciences
Contract value: 9.600.000 lei
Coordinator: Prof. Schneider F., MD, PhD
3. Physiology of tracheobronchial smooth musculature.
Experimental and clinical studies, 1992-1995, Research contract with the Ministry of Education and with the Ministry of Research and Technology
Contract value: 16.300.000 lei
Coordinator: Prof. Schneider F., MD, PhD
4. Monitoring the responsiveness in bronchial asthma. Clinical and experimental study
Clinical and experimental study 2002-2003, Grant A Contract - CNCSIS, Nr. 1331/33454/ 17.07.2002 [i 620/33542/1.07.2003
Grant manager: Prof. Mihalas G., MD, PhD
Contract value: 164.000.000 lei
5. Developing tissual bioenergy techniques for osteo-articular and myocardial reconstruction
Contract with the Ministry of Research and Technology, National Research, Development, and Innovation Programs - the MATNANTECH Programme, No. 162 (303)
Contract value: 2.5 billion ROL(over 60000 EUR)
Grant manager: Prof. Virgil Paunescu, MD, PhD
6. Adult mesenchymal stem cells engineering for connective tissue disorders. From the bench to the bed
side.

FP6 integrated project, GENOSTEM no. 503161
Duration: 2003-2006
Project coordinator for Romania: Prof. Virgil Paunescu, MD, PhD

IV. AFFILIATION TO PROFESSIONAL ASSOCIATIONS
Member of the National Society of Physiological Sciences
Member of the Federation of European Physiological Sciences (FEPS)
Member of the National Society of Cellular Biology

V. OTHER POSITIONS
1. Executive director of Physiology, the official journal of the Romanian Society of Physiological Studies
2. Research projects evaluator, FP6 - within the European Comission, no. EX2002B040593, Health Directorate, Unit 6 - Fundamental Genomics
3. Member of the research team of the Immunophysiology and Biotechnologies Centre, Timisoara, recognized by CNCSIS as type C research centre.

VII. 25 participations in national and international scientific meetings

VIII. WORKS PUBLISHED
Elaboration of 153 scientific works, among which 17 collaborations on course books and monographs, 49 papers published in extenso - 13 articles as first author and 30 as co-author, 85 papers published in abstract volumes of national and international conferences, 8 oral presentations presented during national scientific conventions and not published in volumes of proceedings.

BOOKS PUBLISHED ABROAD
Schneider Fr., Siska Ioana Raluca, Avram J., 'Clinical physiology of the venous system' Kluwer Academic
Publishers (Boston/ Dordrecht/ London) 2003; 303 pages, ISBN 1-4020-7411-5

ARTICLES PUBLISHED IN EXTENSO ABROAD

1. Some aspects concerning the antioxidant capacity of venous blood in lower limbs varicose veins, Oxygen Transport to Tissue XXI
Siska Ioana Raluca, Avram J., Tatu C., Bunu C., Schneider Fr., Maties R., , ed. D. Delpy and A. Eke, Plenum Press NY, 1999, pp. 445-452
2. Les taux de superoxide dismutase et de glutathion
dans le sang des saphenes variqueuses

Avram J., Siska Ioana Raluca, R. Maties, R.Avram, D.Crîsnic, , Phlebologie, 1999; 52 (2), pp. 155-162
3. Endothelial cells obtained from haematopoietic stem cells are functionally different from those obtained from human umbilical vein.
Paunescu V., Suciu E., Tatu C., Plesa A., Herman D., Siska Ioana Raluca, Suciu C., Crîsnic D., Nistor D., Tanasie G., Bunu C., M. Raica, Journal of Cellular and Molecular Medicine, 2003