CARMEN BUNU
I. PERSONAL DETAILS
Family name: BUNU
First name: CARMEN
Date of birth: 06.04.1961
E-mail:cbunu@umft.ro

II. EDUCATION AND QUALIFICATIONS
Associate professor, Dept. of Physiology, Victor Babes University of Medicine and Pharmacy, Timisoara
MD, functional explorations
Specialist in Immunology-Allergology
PhD in Medicine, speciality: normal and pathological physiology,dissertation: 'Bronchial Cellularity and Reactivity' Timisoara University Centre

III. AREAS OF INTEREST IN RESEARCH
I set up the assessment technique of bronchomotive reactivity through the administration (by inhaling) of the broncho-dilator agents, and I am currently completing the work methodology for the assessment technique of bronchomotive reactivity through the administration (by inhaling) of the broncho-constrictor
agents. I have updated the standard interpretation and work techniques of spirographic bulletins.
Study of immunologic aspects in viral hepatitis with special focus on the implication of HLA antigens in the pathology of viral hepatitis
Experimental aspects concerning the protective role of calcium blockers on myocardial fibre in the chronic cardiopathy and the immunologic particularities from the febrile syndromes at valvular patients that have undergone an operation.
I completed the immuno-blotting and immuno-enzymatic techniques (ELISA) used in the field of allergology. The results of the research have been used in the standardization of remedies with allergens for the desensitization of allergic patients and for the setting up of the main antigenic fractions from the structure of the allergens used in producing medications.
Cellular immunity at asthmatic patients compared to those with obstructive chronic broncho-pneumopathies, in parallel with the study of ventilometric and plethysmographic parameters
Flowcitometric study of cellularity from the broncho-alveolar lavage. This approach of the study of cellularity from the broncho-alveolar lavage by marking with monoclonal antibodies was a premiere in Romania.
The comparative effect of some medications at patients with broncho-pulmonary diseases:
- the effect of Salmeterol and of Salbutamol;
- the effect of calcium blockers on Raw at asthmatic patients compared to patients with BPOC and a group of unaffected subjects;
- the effect of inhaling cortico-therapy on symptomatology and on ventilometric parameters at asthmatic patients in parallel with the modifications of cellularity from the broncho-alveolar lavage;
- I presently observe the advantages of complex inhaling-preparations (beta2-sympathomimetic and parasympatholitic) in chronic pulmonary diseases;
- I work together with the colleagues from the discipline Pneumo-phthisiology at the standardization of the investigation algorithm in the stage diagnosis of the bronchial allergy and of the allergic patient;
- I standardized the bronchial stimulation techniques for testing bronchial hyper-responsiveness;
- Haematopoietic and mesenchymal stem-cell.

IV. SCIENTIFIC AWARDS
Abroad:
Bunu, C., Mihalas, G., Tanasie, G., Noveanu, L., Siska, I.R., Vancea, D., Paunescu, V., 2003, Leukotriene
Receptor Antagonist versus Corticotherapy in Airways Responsiveness in Ovalbumin Sensitized Rats, 13th
ERS Annual Congress, Vienna, Austria, European Respiratory Journal, p. 478s - paper awarded with bronze
In Romania:
Schneider, F., Petroiu, A., Mihalas, G., Bunu, C., Siska, I, Tanasie, G., 1998 Bronchomotility in Bronchial Asthma and Broncho-pneumopathies, "Romanian Medical Life" Publishing House, Bucharest 180, ISBN 973-9320-20- book awarded with the prize 'Daniel Danielopolu' by the Academy of Medical Sciences;
F., Petroiu, A., Mihalas, G., (ed), Ed. Viata Medicala Româneasca, Bucuresti, 180, ISBN 973-9320-20- book
awarded with the prize 'Daniel Danielopolu' by the Academy of Medical Sciences.

V. GRANTS
1. Quality and safety assessment in clinical and toxicological application of stem cells
FP6 integrated project, SAFESTEM, section 'Advanced genomics and its applications for health'
Project coordinator for Romania: Assoc. Prof. Carmen Bunu, MD,PhD
2. Adult mesenchymal stem cells engineering for connective tissue disorders. From the bench to the bed side
FP6 integrated project, GENOSTEM no. 503161
Duration: 2003-2006
Project coordinator for Romania: Prof. Virgil Paunescu, MD, PhD
3. Pre-clinic and clinic research on the Romanian product Antagonic-stress
Research contract with POLGEC SRL, Bucharest
Contract value: 2.900.000 lei
Coordinator: Prof. Schneider F., MD, PhD
4. Bronhomotricitatea. Implicatii imuno-alergice - Bronchomotility. Immuno-allergic implications
1992 - 1995, Research contract with the Academy of Medical Sciences
Contract value: 9.600.000 lei
Coordinator: Prof. Schneider F., MD, PhD
5. Physiology of tracheobronchial smooth musculature.
Experimental and clinical studies
1992-1995, Research contract with the Ministry of Education and with the Ministry of Research and Technology
Contract value: 16.300.000 lei
Coordinator: Prof. Schneider F., MD, PhD
6. Monitoring the Bronchial Responsiveness in Asthma
Clinical and experimental study
2002-2003, Grant A Contract - CNCSIS, Nr. 1331/33454/ 17.07.2002 [i 620/33542/1.07.2003
Grant manager: Prof. Dr. Mihalas G.
Contract value: 164.000.000 lei
7. Developing Tissual Bioenergy Techniques for the Osteoarticular and Myocardial Reconstruction
Contract with the Ministry of Research and Technology, National Research, Development, and Innovation Programs - the MATNANTECH Programme, No. 162 (303)
Contract value: 2.5 billions ROL(over 60000 EUR)
Grant manager: Prof. Virgil Paunescu, MD, PhD

IV. AFFILIATION TO PROFESSIONAL ASSOCIATIONS
Member of the European Physiology Society
Member of the European Respiratory Society
Member of the Romanian National Society of Physiological Sciences
Member of the Romanian National Immunology Society
Member of the Romanian Academy of Interdisciplinary Medical Studies
Member of the Romanian National Pneumophtisiology Society

V. OTHER POSITIONS
FP6 expert evaluator (EX2002B039266), sub-comission TP5, Biotechnology, Agriculture and Food, E.2. Food quality
CNCSIS expert evaluator , Nr. 638/2003
Scientific advisor for the scientific bulletin of Victor Babes University of Medicine and Pharmacy, Timisoara, Pre-clinical section
FP6 program coordinator for Victor Babes University of Medicine and Pharmacy, Timisoara
Member of the Immuno-physiology and Biotechnologies Centre, Timisoara

VII. PARTICIPATIONS IN NATIONAL AND INTERNATIONAL CONFERENCES, CONGRESSES, OR CONVENTIONS 25 participations in national and international congresses, conferences or conventions

VIII. WORKS PUBLISHED
Elaboration of 206 scientific works, among which 1 book on bronchial hyper-responsiveness, 24 collaborations at books and speciality monographs, 39 papers published in extenso - 14 as first author and 25 as co-author, 33 papers published in abstract volumes of international conferences proceedings, 79 articles published in abstract volumes of national conferences, 30 oral presentations presented at national or international conferences
and conventions
Ioana Siska, J Avram, C. Tatu, Carmen Bunu, F. Schneider, R. Maties, "Some Aspects Concerning the
Antioxidant Capacity of Venous Blood in Lower Limbs Varicose Veins", Oxygen Transport to Tissue XXI; eds.
D. Delpy and A. Eke; Plenum Press NY; 1999; pp. 445-452